Feed Me the Scoop on Veterinary Feed Directive

Description of in-feed medications and how they fit into the Veterinary Feed Directive (VFD) rules that took effect January 1, 2017.
Feed Me the Scoop on Veterinary Feed Directive - Articles


We are very lucky in this country to have a group of educated, informed individuals ensuring the safety of our food supply. Recent efforts by the Food and Drug Administration (FDA) Center for Veterinary Medicine have addressed reducing the use of "medically important" antibiotics in feeds given to food animals. The newest regulations increase the need for a veterinary feed directive (VFD) statement and are outlined in the FDA document referred to as "Guidance for Industry #213". The VFD order is a written statement issued by a licensed veterinarian to the client (owner or other caretaker of the animal) to obtain and use animal feed containing a VFD drug. The VFD order is essentially a prescription issued by a veterinarian that allows producers to include a medically important antibiotic in feed.

This regulation is specific to the feed or water supply containing the VFD drug, not to the type of animal that consumes the feed. The same regulation applies to dairy, deer, and ducks. No animals are excluded. The regulations will affect all livestock producers who wish to purchase feed-grade antibiotics, regardless of operation size, as of January 1, 2017. Single animal owners and CAFOs (Concentrated Animal Feed Operations) fall under the same directive from the FDA. Keep in mind that extra-label use of feed-grade antibiotics is not acceptable.

VFD orders have an expiration date and may indicate they are good for repeated purchases but may not exceed 6 months. Similar to a prescription, those "refills" will be limited. Education and understanding will fall on all animal owners, regardless of operation size or age. Livestock owners will have to be proactive to prevent "gaps" in their feeding practices created by running low on medicated feed only to discover that the VFD has expired. Check your labels now for medically important drugs. These regulations reach into water-soluble drugs that are transitioning from OTC (over-the-counter) to prescription (Rx).

Hobby farmers or smaller operations associated with some 4-H and FFA participants may feel the impact of the regulations more than larger producers, because smaller producers often obtain veterinary assistance only when there's a medical problem. Veterinarians who are already stretched too thin across some areas of Pennsylvania will have to make some adjustments for the increased VFD demand. The positive impact will be greater attention and understanding surrounding the use of medicated feeds and more responsibility on the part of each animal owner to document medication use. The negative impact is the possibility of an increase in the number of sick and even dead animals, especially where medicated feeds are a vital part of disease prevention.

Many 4-H and FFA participants have been advised to raise their animals using a preventive approach. Instead of waiting until animals get sick, the animals are fed antibiotics during periods of stress when they are most likely to get sick. Young animals are very susceptible to diseases when they are in the primary stages of life. Early in the infection progression, it can be difficult to detect the sickness and treat it in time to save the animal. This becomes a biosecurity issue as efforts will have to be stepped up to keep disease from spreading within the farm and to other farm families.

Inexperienced youth producers may be less likely to notice a disease in the early stages when a cure is most easily accomplished. Details such as reduced appetite or a listless gait could indicate the early onset of illness. Not all 4-H and FFA participants have the experience or observation skills to recognize these details. Even families who know what to look for may find themselves in the "weekend window" or "holiday hold" where quickly obtaining a VFD or medicated feed order will be next to impossible.

The take home message here is be proactive. Be deliberate in your observation of your animals. Track your observations in a journal or on a white board. Talk to your veterinarian and your feed mill and get a clear understanding of the procedure for getting a VFD. Veterinary practices will differ depending on staffing and technology for writing and transmitting a VFD. Above all, increase your biosecurity measures via best management practices that will decrease the risk of disease.

Effective January 1, 2017, a Veterinary Feed Directive (VFD) Order must be presented to purchase feeds containing the medications in Table 1.

Table 1. The Pennsylvania State Department of Agriculture provides the following list of medications, for which a Veterinary Feed Directive (VFD) Order must be presented to purchase feeds containing the medications, effective January 1, 2017.
Established Drug NameExamples of Proprietary Drug Names
* VFD drug prior to January 1, 2017.
Apramycin, Erythromycin, Neomycin (alone), Oleandomycin, Sulfamerazine, and Sulfaquinoxaline are also transitioning to VFD status; however, they are not marketed at this time.
When a VFD drug is used in combination with a non-VFD drug, the feed would require a valid VFD prior to distribution to or use by the end-user.
Chlortetracycline (CTC)Aureomycin, CLTC, CTC, Chloratet, Chlorachel, ChlorMax, Chlortetracycline, Deracin, Inchlor, Pennchlor, Pfichlor
Chlortetracycline/SulfamethazineAureo S, Aureomix S, Pennchlor S
Chlortetracycline/Sulfamethazine/PenicillinAureomix 500, Chlorachel/Pficlor SP, Pennchlor SP, ChlorMax SP
Florfenicol*Aquaflor, Nuflor
Hygromycin BHygromix
Oxytetracycline (OTC)TM, OXTC, Oxytetracycline, Pennox, Terramycin
Oxytetracycline/NeomycinNeo-Oxy, Neo-Terramycin
PenicillinPenicillin, Penicillin G Procaine
Sulfadimethoxine/OrmetoprimRofenaid, Romet
Tilmicosin*Pulmotil, Tilmovet
TylosinTylan, Tylosin, Tylovet
Tylosin/SulfamethazineTylan Sulfa G, Tylan Plus Sulfa G, Tylosin Plus Sulfamethazine
VirginiamycinStafec, Virginiamycin, V-Max

Some medications will not require a VFD at this time, as shown in Table 2.

Table 2. Drugs that are not affected by the Veterinary Feed Directive (VFD) at this time, according to Texas A&M AgriLife Extension Educators. Most commonly used products are listed.
Established Drug NameExamples
In situations where a combination of a medically important drug and a non-medically important drug/hormone are fed together, a VFD is required. Example: Cattle feed with Rumensin and Tylan together in the same bag will need a VFD, whereas cattle fed with just Rumensin will not need a VFD.
Injectable medicationsNo injectable products affected
IonophoresMonensin (Rumensin)
AnthelmeticsIvermectin, Fenbendazole (Safeguard)
Beta agonistsRactopamine (Paylean)
CoccidiostatsDecoquinate (Deccox)